Showing the latest 251 publications
Publications 221-230 of 251
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Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles
Esposito, L., Hunter, K., Clark, J., Rainbow, D., Stevens, H., Denesha, J., et al.
Journal of Immunology (Baltimore, Md.: 1950)
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A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes
Ferreira, R., Guo, H., Coulson, R., Smyth, D., Pekalski, M., Burren, O., et al.
Diabetes
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Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients
Downes, K., Marcovecchio, M., Clarke, P., Cooper, J., Ferreira, R., Howson, J., et al.
Diabetologia
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The IL23R A/Gln381 allele promotes IL-23 unresponsiveness in human memory T-helper 17 cells and impairs Th17 responses in psoriasis patients
Di Meglio, P., Villanova, F., Napolitano, L., Tosi, I., Terranova Barberio, M., Mak, R., et al.
The Journal of Investigative Dermatology
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FOXO in the hole: leveraging GWAS for outcome and function
Gregersen, P., Manjarrez-Orduño, N.
Cell
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Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway
Lee, J., Espéli, M., Anderson, C., Linterman, M., Pocock, J., Williams, N., et al.
Cell
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Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
Hunt, K., Mistry, V., Bockett, N., Ahmad, T., Ban, M., Barker, J., et al.
Nature
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Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases
Ferreira, R., Freitag, D., Cutler, A., Howson, J., Rainbow, D., Smyth, D., et al.
PLoS genetics
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Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors
Pekalski, M., Ferreira, R., Coulson, R., Cutler, A., Guo, H., Smyth, D., et al.
Journal of Immunology (Baltimore, Md.: 1950)
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Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes
Wallace, C., Rotival, M., Cooper, J., Rice, C., Yang, J., McNeill, M., et al.
Human Molecular Genetics