CMV infection in inflammatory bowel disease

Study code
NBR22

Lead researcher
Prof. Holm Uhlig

Study type
Samples and data

Institution or company
University of Oxford

Speciality area
Gastroenterology, Infection

Summary

Cytomegalovirus (CMV) infection has a massive – but subclinical - impact on host immunity, Despite its long association with the gut, however, little is known about its impact in the steady state and interaction with genetic risk factors.

We aim to replicate and confirm findings that CMV infection is associated with the development of ulcerated colitis (UC) and to define the relationship to known UC genetic risk factors.