Antibody responses to AZD-1222 immunisation

Study code
NBR160

Lead researcher
Michelle Linterman, William Foster

Study type
Samples and data

Institution or company
Babraham Institute

Researcher type
Academic-led

Speciality area
Unassigned

Summary

Vaccines can provide protection against infection and disease through the production of pathogen neutralising antibodies. However, some people are less able to generate effective antibody responses upon immunisation due to their genes. In this study we wish to use the NIHR COVID BioResource to access samples from healthy volunteers immunised with AZD-1222 to compare their antibody responses to people who have known changes in their genes that may contribute to poor antibody responses upon vaccination.