COVID-19 IDentification of Epitopes and Antibodies (COVID-IDEA)

Study code
NBR102

Lead researcher
Professor Andrew Cope

Study type
Participant re-contact

Institution or company
King's College London

Speciality area
Infection

Summary

The COVID-19 pandemic has seen an unprecedented number of research studies initiated and rolled out across the globe. Much of the research has focused on characterising the disease and defining therapeutic strategies for the acute infectious event, largely because they have imposed a considerable burden on health systems across the world. Here, we propose to undertake an in-depth analysis of the antigenic specificities recognised by the immune system in patients from across a spectrum of disease phenotypes and severity. The results will provide new insight into the molecular nature of host immunity, and will begin to establish the features that constitute herd immunity and immune memory. We hope to generate data that will identify specific characteristics of subsets of immune effector cells that may have been responsible for some of the devastating outcomes suffered by patients during the first wave of the pandemic.