Recruitment of healthy volunteers from the Cambridge BioResource to understand the function of immune pathways predisposing to autoimmune disease. 

Study code
CBR66

Lead researcher
Professor Tim Vyse

Study type
Participant re-contact

Institution or company
King`s College London

Researcher type
Academic

Speciality area
Cross-cutting

Recruitment Site
Cambridge

Summary

We are studying the autoimmune disease Systemic Lupus Erythematosus (SLE), which affects mainly young people and can cause a range of problems including skin rashes, arthritis, kidney disease and brain disease.

Although the cause of this disease is so far unknown, we know that genes (currently about 50 have been identified) are important in this process. Understanding how these genes control the cells and proteins of the immune system will give us important information about where to look to understand further what is happening in patients with disease, and therefore which parts of the immune system could be targeted with new treatments.