Genetic and cellular mechanisms protecting from tuberculosis

Study code
CBR22

Lead researcher
Dr Sergey Nejentsev

Study type
Participant re-contact

Institution or company
University of Cambridge

Researcher type
Academic

Speciality area
Infection

Recruitment Site
Cambridge

Summary

The purpose of this study is to find the genes and to understand biological mechanisms that are involved in protecting humans from infectious diseases, in particular, from tuberculosis. Tuberculosis remains a global health problem. Every year there are approximately 9 million new patients and more than 1 million deaths due to tuberculosis. Currently available vaccine called BCG does not prevent pulmonary tuberculosis, the most common form of the disease. New, more efficient vaccines are required. However, to design such vaccines researchers need to better understand biological mechanisms of infection and immunological protection against it. Our study is designed to collect this valuable information.