CADBIO – Molecular investigation of Genetic Factors in Cardiovascular Diseases Using a BioResource of Healthy Volunteers

Study code
CBR202

Lead researcher
Dr Dirk Paul

Study type
Participant re-contact

Institution or company
Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge

Researcher type
Academic

Speciality area
Cardiovascular Disease

Recruitment Site
Cambridge

Summary

Genome-wide association studies (GWASs) have identified a number of genetic variants associated with cardiovascular diseases (e.g. coronary heart disease) and their causal risk factors such as blood pressure and cholesterol levels). However, the precise molecular mechanisms underlying the majority of the implicated genetic variants have remained elusive. Dirk’s research team aims to uncover more about the impact of these variants on the biology of cardiovascular diseases, which is fundamental for developing therapeutic strategies.