CAM-SAFE 

Study code
CBR126

Lead researcher
Joanne Jones

Study type
Participant re-contact

Institution or company
University of Cambridge

Researcher type
Academic

Speciality area
Neurological Disorders

Recruitment Site
Cambridge

Summary

Multiple sclerosis and Type 1 diabetes are examples of autoimmune diseases. They occur when the immune system (which is there to fight infection) mistakenly attacks its own tissues. In healthy individuals regulatory cells (called Tregs for short) normally prevent this from happening.

The aim of this study is to understand why Tregs fail to control the immune system in individuals with autoimmunity. We will also examine the effect of prescribed medications (such as alemtuzumab for MS) on Tregs.

 

Participation: For this study we 10 patients from the Cambridge BioResource who have been diagnosed with Type 1 Diabetes and were between the ages of 18 and 50. Volunteers attended a single appointment to give a 90ml blood sample.

Organisation: This study is organised by Dr Joanne Jones from the Department of Clinical Neurosciences at the University of Cambridge.