Developmental Origins of Type 2 Diabetes: Tolerance of Fasting and IGF-I Levels

Study code

Lead researcher
Professor David Dunger

Study type
Participant re-contact

Institution or company
University of Cambridge

Researcher type

Speciality area

Recruitment Site


The purpose of this study is to find out whether reduced blood levels of the naturally occurring hormone Insulin-like Growth Factor-I (IGF-I), that regulates growth and metabolism, are associated with reduced insulin production and function.

This information would be useful in understanding the mechanisms that might lead to the development of type 2 diabetes, a chronic disease characterised by reduced insulin production and action.

Participation: For this study we recruited 19 volunteers from the Cambridge BioResource to an overnight stay at the clinical research facility at Addenbrooke's hospital. During the visit volunteers, gave blood samples, had an MRI scan and tests relating to how fast body fat and sugar is used. 

Organisation: This study is organised by Professor David Dunger from the School of Clinical Medcine and the University of Cambridge.