Mental Health BioResource

A re-contactable mental health bioresource comprised of participants who have provided rich phenotypic information and genetic data.

Graphic of profiles of heads to represent mental health

About the Mental Health BioResource

The NIHR BioResource for Mental Health focuses on recruiting participants experiencing mental health conditions, as well as healthy controls.

Genetic Links to Anxiety and Depression (GLAD) is the largest such bioresource and has extensive phenotypic information and genetic data.

Depression and anxiety are the most common mental health disorders worldwide. In the UK, 1 in 3 people will experience symptoms during their lifetime. The GLAD Study aims to better understand depression and anxiety in order to find effective treatments and improve the lives of people experiencing these disorders.

Recruitment as of June 2024:

  • 62,000 participants consented
  • 50,000 questionnaire responses submitted
  • 35,000 saliva sample kits returned

This year, we have launched recruitment for a 'control group' (participants without a mental health diagnosis) and aim to recruit 10,000 individuals.

GLAD image

A similar approach is being used to recruit participants to the Eating Disorders Genetics Initiative (EDGI). Apart from those with anorexia we also recruit conditions such as bulimia, binge eating and non-specified eating disorders.

Our aim is to collect the psychological, medical, and genetic information of 10,000 people with experience of any eating disorder. This will help us to better understand the role both our genes and environment play in the development of these illnesses.

Recruitment as of June 2024:

  • 13,000 participants consented
  • 9,000 questionnaire responses submitted
  • 5,100 saliva sample kits returned

COVID

In response to the pandemic we launched multiple COVID19-related projects:

  • COVID-19 Psychiatry and Neurological Genetics (COPING) study: assessing mental health during the pandemic
  • COVID-CNS study: research into acute neurological effects of COVID-19, providing vital information about the interrelationship between infection and psychiatry
View of lab with microscope, brain scans and DNA on screen
Close-up of keyboard with 'Contact us' written on one of the keys

Contact information 

bioresource@kcl.ac.uk

Our Centres and Programmes

The NIHR BioResource is a network of Centres that recruit participants locally and lead research programmes.

More about our Centres and Programmes