The human genome can be written as a sequence of 3 billion letters, using only the letters A, C, G and T in a specific order. Over 99% of this sequence order is identical between individuals; however, there are some spots in the genome where the letters differ between individuals. These genetic differences, in combination with environmental factors, determine what makes us unique and different. Importantly, they also determine our risk of contracting a specific disease, how the disease will progress, or how well we respond to treatment. Enhanc3D Genomics’ founders have invented a molecular biology technique that allows us to understand the function of these sequence changes in the three-dimensional space of the nucleus, where the human genome is stored within cells. Equipped with this information, the Enhanc3D Genomics team can embark on new approaches to understand the molecular mechanisms underlying a broad range of diseases, to identify new drug targets for disease treatment, and to design treatment regimes that are specifically for individual patients.
