IBD drug therapies and COVID-19

Study code
DAA042

Lead researcher
Nick Kennedy

Study type
Data only

Institution or company
Cambridge University Hospitals NHS Foundation Trust

Researcher type
Academic

Speciality area
Gastroenterology, Infection, COVID

Summary

Our aim is to see whether the immunosuppressant drugs used to treat a high proportion of patients with IBD increase the risk of contracting COVID19, and/or whether they increase the risk of adverse outcomes for those who do become infected. The comparison will be against IBD patients on other drugs or none. The IBD BioResource participants have provided consent to access their health records, and this research will require a combination of a number of linked data sources – some of which need additional permissions.

Proposed data sources are: Public Health England (SARS-Cov2 test results, hospital admission and outcome); NHS Digital (hospital treatments); IBD Registry (the IBD Registry Risk Stratification Tool, patient-reported medications); and CPRD (primary care data), amongst others.