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study

Comparing the study drug GSK1521498 against a licensed drug (naltrexone), and a placebo, in reactions to food and alcohol cues

Lead: Professor Pradeep Nathan

Mental Health

publication

SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity

Cell Reports
Meng, B., Datir, R., Choi, J., Bradley, J., Smith, K., Lee, J., et al.

3 August 2022

study

Neuronal mechanisms underlying the role of serotonin and its genetic polymorphism on compulsive behaviours

Lead: Professor Trevor W. Robbins

Mental Health

study

Examining what factors influence food choices and preferences in adults

Lead: Dr Suzanna Forwood

Unassigned

study

Generation of Donor Induced Pluripotent Stem (IPS) Cells for Research

Lead: Professor Roger Pederson

Haematology

publication

Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans

eLife
Lemmelä, S., Wigmore, E., Benner, C., Havulinna, A., Ong, R., Kempf, T., et al.

2 August 2022

publication

Inflammatory bowel disease patient-reported quality assessment should drive service improvement: a national survey of UK IBD units and patients

Alimentary Pharmacology & Therapeutics
Hawthorne, A., Glatter, J., Blackwell, J., Ainley, R., Arnott, I., Barrett, K., et al.

1 August 2022

study

BDNF gene neuroplasticity study

Lead: Professor Pradeep Nathan

Dementias and Neurodegeneration

study

Time course and determinants of arterial stiffening

Lead: Professor Kevin O’Shaughnessy

Cardiovascular Disease

study

Long-term safety and mechanism of action of Alemtuzumab in the treatment of Multiple Sclerosis

Lead: Professor Alasdair Coles

Neurological Disorders

study

How does dopamine influence social decision making in healthy male volunteers

Lead: Professor Christoph Eisenegger

Neurological Disorders

study

Investigation of phenotypes associated with genetic variants of metabolic interest (IPGMI)

Lead: Professor Sir Stephen O&amp

Genomics and Rare Diseases
Metabolic and Endocrine Disorders

study

Boosting vaccine responses in older persons

Lead: Dr Michelle Linterman

Ageing
Infection
Primary Care

study

Genetic Analysis of Platelets in Healthy Individuals (PASHA)

Lead: Professor Willem Ouwehand

Cardiovascular Disease
Haematology

study

Primary Biliary Cirrhosis (PBC): identification of genes associated with liver disease.

Lead: Professor Richard Sandford

Liver

study

Genotype and Phenotype in Inherited Neurodegenerative Diseases

Lead: Professor Patrick Chinnery

Neurological Disorders
Infection

study

Generation of Patient-Specific Stem Cells for Research into Stroke

Lead: Professor Hugh Markus

Stroke

publication

Depression, anxiety and PTSD symptoms before and during the COVID-19 pandemic in the UK

Psychological Medicine
Young, K., Purves, K., Hübel, C., Davies, M., Thompson, K., Bristow, S., et al.

26 July 2022

study

Modulating Emerging Memory Responses to Immunisation (MEMRI)

Lead: Dr Eoin McKinney

Infection
Primary Care
Ageing

publication

MED27, SLC6A7, and MPPE1 Variants in a Complex Neurodevelopmental Disorder with Severe Dystonia

Movement Disorders: Official Journal of the Movement Disorder Society
Reid, K., Spaull, R., Salian, S., Barwick, K., Meyer, E., Zhen, J., et al.

22 July 2022

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