The Oxford BioResource will be a prominent resource within the cardiovascular and metabolic research community as well as an invaluable resource for National Institute for Health Research (NIHR) BioResource, drawing on a well characterised local population ready to participate in translational research.
Among the first of the bioresources, Oxford established the Oxford BioBank (OBB) in 2000 and to date have recruited 7,800 healthy men and women randomly selected within the age range of 30 to 50 years, and now growing at a rate of 1,000 per year. Recorded on all OBB volunteers is a rich set of diabetes/obesity and cardiovascular related anthropometric and biochemical measurements, together with IlluminaExomeSNP Chip analysis and NMR Melabolomic analysis, currently on the first 5,900 participants. Affymetrix Axiom UK BioBank Array data will also be available on 7300 participants as of 2016. In addition to healthy controls, in 2015 the Oxford Biobank started recruiting Type II Diabetics.
In addition to the OBB, other cohorts coming under the Oxford BioResource umbrella include:
OXVASC (Oxford Vascular Study, n=1,100), a population based cohort collecting heart attack and other acute vascular end points.
YDX (Young Diabetes in Oxford, n=1,600), established to examine the etiological basis of diabetes in early adulthood.
The OPDC Discovery Cohort (http://opdc.medsci.ox.ac.uk, n=1,000), a Parkinson disease cohort focused on the better understanding of how Parkinson’s disease progresses in different ways in different people,
AdipoRedox (n=900) is a cohort of heart disease patients undergoing coronary bypass artery grafting or valve replacement surgery.
ENDOX (n=300) is a cohort of women with endometriosis undergoing laparoscopy. Oxford BioResource is part of the NIHR Oxford Biomedical Research Centre which is a collaboration between University of Oxford and Oxford University Hospitals. .
Oxford BioResource is part of the NIHR Oxford Biomedical Research Centre which is a collaboration between University of Oxford and Oxford University Hospitals.